Title: Lentiviral vectors and uses thereof
Priority patent application: PCT/ES2021/070343
Inventors: Juan Antonio Bueren Roncero; Susana Navarro Ordóñez; Yari Giménez Martínez; Manuel Palacios Pérez; Denis Lafontaine 
Aplicants: CIEMAT/FJD/CIBER and Université Libre de Bruxelles and Hospital Infantil Universitario Niño Jesús
PCT:  ES2021/070343

Title: Methods for Gene Modification of Hematopoietic Cells
Priority patent application: US 62/712,146
Inventors: Juan Bueren; José Carlos Segovia; Paula Rio Galdo; Susana Navarro Ordóñez; Elena Almarza Novoa; Oscar Quintana Bustamante; Cristina Mesa 
Aplicants: CIEMAT/FJD/CIBER and Rocket Pharmaceuticals
PCT:  US2019/44237

Title: Improvements for performing and facilitating the recovery after hematopoietic stem cell transplantation
Priority patent application: EP18382779
Inventors: Oscar Quintana, José Carlos Segovia, Juan Bueren  
Aplicants: CIEMAT/FJD/CIBER
PCT:  EP2019/079945

Priority patent application: US 62/573,037
Inventors: Juan Bueren, Susana Navarro,  Jose Carlos Segovia, María García Gómez, Nestor Meza, María García Bravo 
Aplicants: CIEMAT/FJD/CIBER
PCT: US2018/056136

Title: Gene Therapy for patients with Fanconi anemia
Priority patent application: US 62/385,185
Inventors: Juan Bueren, Guillermo Guenechea, Julian Sevilla, Susana Navarro, Paula Río, Jose Carlos Segovia, Jose Antonio Casado, África González Murillo
Aplicants: CIEMAT/FJD/CIBER
PCT: US2017/050837

Title: Compositions and methods for enhanced gene expression of PKLR
Priority patent application: US 62/325.397
Inventors: Jose C. Segovia, María Garcia-Gomez, Susana Navarro, Nestor W. Meza, Juan A. Bueren, María Garcia-Bravo
Aplicants: CIEMAT/FJD/CIBER
PCT: US2017/028695

Title: Process of gene-editing of cells isolated from a subject suffering from a metabolic disease affecting the erythroid lineage, cells obtained by said process and uses thereof.
Priority patent application: EP15382545
Inventors: Jose C. Segovia, Óscar Quintana Bustamante, Zita Maite Gárate Mutiloa, Juan Antonio Bueren Roncero, Brian R. Davis. 
Aplicants: CIEMAT/FJD/CIBER
PCT: EP2016/076893

Title: Generation of genetically corrected disease-free induced pluripotent stem cells
Priority patent application: US20090181287P
Inventors: Ángel Raya, Juan Antonio Bueren, Juan Carlos Izpisúa-Belmonte
Aplicants:: The Salk Institute for Biological Studies/ Center of Regenerative Medicine of Barcelona
PCT: US2010/036456

Title: Expression vectors which include the human pklr gene promoter and use thereof for preparing pharmaceutical compositions for somatic genetic therapy with specific expression in erythroid cells
Priority patent application: P20070001024
Inventors: José Carlos Segovia-Sanz, Néstor W Meza; Juan Antonio Bueren, Elena Almarza-Novoa, Guillermo Güenechea-Amurrio y María Eugenia Alonso-Ferrero
Aplicants: CIEMAT
PCT: ES2008/070069

Title: Expression vectors comprising the HS1 promoter of the VAV1 oncogene and use thereof for the preparation of pharmaceutical compositions intended for somatic gene therapy
Priority patent application:: ES20060001477
Inventors: Elena Almarza, Montserrat Aldea, Guillermo Güenechea, José Carlos Segovia, Juan Antonio Bueren
Aplicant: CIEMAT
PCT: EP2007/055368

Title: Use of adipose derived mesenchymal stem cells for the treatment of graft versus host disease.
Priority patent application: EP20050380266
Inventors: Manuel Ángel González de la Peña, Juan Antonio Bueren, Rosa María Yáñez-González, María Luisa Lamana-Luzuriaga, Dirk Büscher y Aitor Beraza-Pérez
Aplicants: CIEMAT/CELLERIX
PCT: EP2006/069426